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The following terms were not found in PubMed: 0102400ORlysophospholipase, pseudogeneANDPlasmodium
Page 1
Characterization of Plasmodium falciparum prohibitins as novel targets to block infection in humans by impairing the growth and transmission of the parasite.
Saini M, Ngwa CJ, Marothia M, Verma P, Ahmad S, Kumari J, Anand S, Vandana V, Goyal B, Chakraborti S, Pandey KC, Garg S, Pati S, Ranganathan A, Pradel G, Singh S. Saini M, et al. Biochem Pharmacol. 2023 Jun;212:115567. doi: 10.1016/j.bcp.2023.115567. Epub 2023 Apr 22. Biochem Pharmacol. 2023. PMID: 37088154
Prohibitins (PHBs) are highly conserved pleiotropic proteins as they have been shown to mediate key cellular functions. Here, we characterize PHBs encoding putative genes ofPlasmodium falciparum by exploiting different orthologous models. We demonstrated that PfPHB1 …
Prohibitins (PHBs) are highly conserved pleiotropic proteins as they have been shown to mediate key cellular functions. Here, we characteriz …
New lignan glycosides from Justicia secunda Vahl (Acanthaceae) with antimicrobial and antiparasitic properties.
Kamlo Kamso VF, Dongmo Melogmo YK, Tchegnitegni BT, Tchatat Tali MB, Dize D, Ngansop CN, Ambassa P, Ouete Nantchouang JL, Konga IS, Boyom FF, Ngadjui BT, Fotso GW. Kamlo Kamso VF, et al. Heliyon. 2023 Nov 27;9(12):e22897. doi: 10.1016/j.heliyon.2023.e22897. eCollection 2023 Dec. Heliyon. 2023. PMID: 38125494 Free PMC article.
Furthermore, the antiplasmodial, antileishmanial, and antitrypanosomal activities were assessed against the sensitive (3D7) and multidrug-resistant (Dd2) strains of P. falciparum, promastigote and bloodstream forms of L. donovani, and Trypanosoma brucei, respectivel …
Furthermore, the antiplasmodial, antileishmanial, and antitrypanosomal activities were assessed against the sensitive (3D7) and multi …
Generation of Novel Plasmodium falciparum NF135 and NF54 Lines Expressing Fluorescent Reporter Proteins Under the Control of Strong and Constitutive Promoters.
Miyazaki S, Yang ASP, Geurten FJA, Marin-Mogollon C, Miyazaki Y, Imai T, Kolli SK, Ramesar J, Chevalley-Maurel S, Salman AM, van Gemert GA, van Waardenburg YM, Franke-Fayard B, Hill AVS, Sauerwein RW, Janse CJ, Khan SM. Miyazaki S, et al. Front Cell Infect Microbiol. 2020 Jun 10;10:270. doi: 10.3389/fcimb.2020.00270. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 32587831 Free PMC article.
Transgenic reporter lines of malaria parasites that express fluorescent or luminescent proteins are valuable tools for drug and vaccine screening assays as well as to interrogate parasite gene function. Different Plasmodium falciparum (Pf ) reporter lines exist, however ne …
Transgenic reporter lines of malaria parasites that express fluorescent or luminescent proteins are valuable tools for drug and vaccine scre …
The Multistage Antimalarial Compound Calxinin Perturbates P. falciparum Ca(2+) Homeostasis by Targeting a Unique Ion Channel.
Gupta Y, Sharma N, Singh S, Romero JG, Rajendran V, Mogire RM, Kashif M, Beach J, Jeske W, Poonam, Ogutu BR, Kanzok SM, Akala HM, Legac J, Rosenthal PJ, Rademacher DJ, Durvasula R, Singh AP, Rathi B, Kempaiah P. Gupta Y, et al. Pharmaceutics. 2022 Jun 28;14(7):1371. doi: 10.3390/pharmaceutics14071371. Pharmaceutics. 2022. PMID: 35890267 Free PMC article.
Calxinin exhibits potent inhibitory activity in the nanomolar range against the asexual blood stages of drug-sensitive (3D7), multidrug-resistant (Dd2), artemisinin-resistant (IPC4912), and fresh Kenyan field isolated Plasmodium falciparum strains. ...A computationa …
Calxinin exhibits potent inhibitory activity in the nanomolar range against the asexual blood stages of drug-sensitive (3D7), multidr …
Population genetic and biophysical evidences reveal that purifying selection shapes the genetic landscape of Plasmodium falciparum RH ligands in Chhattisgarh and West Bengal, India.
Ghoshal S, Chowdhury P, Ray S, Mitra M, Kanjilal SD, Sen S, Dasgupta AK, Sengupta S. Ghoshal S, et al. Malar J. 2020 Oct 14;19(1):367. doi: 10.1186/s12936-020-03433-z. Malar J. 2020. PMID: 33054833 Free PMC article.
It simultaneously evaluates a putative gain-of-function variant of PfRH5, a keystone member of PfRH family. ...The majority of extant PfRH5 sequences (52/83) differed from the reference Pf3D7 allele by a single amino acid mismatch (C203Y). This non-conservative alte …
It simultaneously evaluates a putative gain-of-function variant of PfRH5, a keystone member of PfRH family. ...The majority of extant …